The hearing is slated to begin at 7 p.m. at the Chapel Hill Town Hall.
All aspects of the Development Plan, which details campus growth for the next eight years, will be open for discussion. The plan is a part of Master Plan, a 50-year blueprint for growth.
Jonathan Howes, special assistant to the chancellor for University relations, will present the Development Plan and answer questions residents might have.
Howes said he expects resistance over an affidavit the University filed Friday, requesting that it be released from zoning restrictions at the Smith Center.
"We have asked the town to vacate the special-use permit," he said.
Under a special-use permit approved in 1980, the University must provide a vegetative buffer between the Smith Center and the Mason Farm Road neighborhood.
But, according to the University's affidavit, a proposed student family housing complex at the southern perimeter of campus will "provide an equally effective buffer" between the Smith Center and the Mason Farm Road neighborhood.
Howes said the type of housing proposed will blend in well with the neighborhood. "Our position is that circumstances have changed since that permit was adopted," he said. "We expect resistance."
Council members also have flagged the Mason Farm issue as a likely point of debate.